医学考博每日一读：Huntington's disease 'lowers' cancer risk

会计考友

医学考博每日一读：Huntington's disease 'lowers' cancer risk
People with Huntington's disease, a debilitating brain condition, appear have a "protection" from cancer, according to a study in Sweden.
3 v8 n* g7 [& X; F! f- J' ]/ F3 D0 `# I- ONearly 40 years of medical records showed patients with Huntington's had half the normal expected risk of developing tumours.
# G1 q6 |& R, ]$ k: b. Z# f- V, WResearchers, writing in The Lancet Oncology, said the reason was unclear.
% s2 o( q9 Q+ z' Q; t1 {Cancer Research UK said the findings presented another avenue to explore in tackling cancer.
Academics at Lund University analysed Swedish hospital data from 1969 to 2008. They found 1,510 patients with Huntington's disease.
1 k; s: ^. V4 _During the study period, 91 of those patients subsequently developed cancer. The authors said that was 53% lower than the levels expected for the general population.
+ @& S/ v  ?/ @7 n/ R$ bHuntington's is one of a group of illnesses called "polyglutamine diseases". Data from other polyglutamine diseases also showed lower levels of cancer.
The authors said: "We found that the incidence of cancer was significantly lower among patients with polyglutamine diseases than in the general population.
2 Q$ ?# ]6 F/ m) Y7 ?"The mechanisms behind the protective effects against cancer are unclear and further research is warranted."
Eleanor Barrie, senior science information officer at Cancer Research UK, said: "These are interesting results. It's not clear how the genetic changes that cause Huntington's and other similar diseases could protect against cancer, and research in the lab will help to find out more.
"Scientists at Cancer Research UK and around the world are probing the genetic faults that contribute to cancer in their quest to beat the disease, and this is another potential avenue to explore."
" F7 V" T! O; `, R6 K2 J
% J- g9 j3 b* V) E& T- e# j医学考博英语复习用书推荐>>
! f. y, z  G3 r8 P, y/ G& `. h医学考博英语一本通：http://www.c2cedu.cn/goods.php?id=1326
医学考博英语真题全国医学博士英语统考真题：http://www.c2cedu.cn/goods.php?id=2412
( V" Z$ I% m/ D( H* h' G名师传授医学考博英语复习备考方案：http://www.b2cedu.com/product/PR000082
医学考博英语复习资料免费下载：http://www.b2cedu.com/down?t=1113.0