Once-daily pill could simplify HIV treatment
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6 U9 J7 f. J7 L! A t. pMyers Squibb and Gilead Sciences have combined many H.I.V. drugs into a single pill Sometimes the best medicine is more than one kind of medicine. Malaria, tuberculosis and H.I.V./AIDS,2 for example, are all treated with ____1____ of drugs. But that can mean a lot of pills to take. It would be ____2____ if drug companies combined all the medicines into a single pill, taken just once a day.
4 F/ d8 G1 t( S& F. B% ENow, two companies say they have done that for people just ____3____ treatment for H.I.V., the virus that causes AIDS. The companies are Bristol-Myers Squibb and Gilead Sciences. They have ____4____ a single pill that combines three drugs currently on the market.3 Bristol-Myers Squibb sells one of them ____5____ the name of Sustiva.4 Gilead combined the ____6____, Emtriva and Viread, into a single pill in two thousand four. 0 |1 q; b3 @( Y5 b8 u
Combining drugs involves more than ____7____ issues. It also involves issues of competition ____8____ the drugs are made by different companies. The new once-daily pill is the result of ____9____ is described as the first joint venture agreement of its kind in the treatment of H.I.V.
; A* _! r3 \/ {. E- BIn January the New England Journal of Medicine5 published a study of the new pill. Researchers compared its ____10____ to6 that of the widely used combination of Sustiva and Combivir. Combivir ____11____ two drugs, AZT7 and 3TC.8 The researchers say that after one year of treatment, the new pill suppressed H.I.V. levels in more patients and with ____12____ side effects.9 Gilead paid for the study. Professor Joel Gallant at the Johns Hopkins School of Medicine in Baltimore, Maryland, led the research. He is a paid adviser to Gilead and Bristol-Meyers Squibb as well as the maker of Combivir, GlaxoSmithKline.
* [9 L5 [- v: E& P5 ~0 R3 lGlaxo Smith Kline reacted ____13____ the findings by saying that a single study is of limited value. It says the effectiveness of Combivir has been shown in each of more than fifty studies.
( w+ c& s9 O8 T# q- i `, zThe price of the new once-daily pill has not been announced. But Gilead and Bristol-Myers Squibb say they will provide it at reduced cost to developing countries. They plan in the next few months to ask the United States Food and Drug Administration10 to ____14____ the new pill. ! u- c& s3 D( h3 H; \# Y) q- [
There are limits to who could take it because of the different drugs it contains. For example, ____15____ women are told not to take Sustiva because of the risk of birth disorders.11 Experts say more than forty million people around the world are living with H.I.V.# \% V9 C% ]5 U( L8 L' q9 K
/ V& P' z& O7 P7 I0 E' l2 L$ t& W词汇:! F" C) X7 [3 r' ], j% \- q7 z
malaria n. 疟疾& _1 k% y3 L: C9 k8 w9 L1 d3 O
tuberculosis n. 结核(病)
, C |/ b# E1 N4 h. U. Mjoint adj. 联合的,共同的( x5 w/ z/ e1 `2 o
suppress vt. 抑制来源:中国职称英语考试网
5 F5 v- S4 L- z5 ]9 Zpregnant adj. 妊娠的,有孕的! [* Y1 O u- O( x0 v
/ N4 @, [. f4 c- M: s& d, J注释:
4 S- X$ e4 B# I+ G9 W5 Q; P1. HIV ( human immunodeficiency virus ):人免疫缺陷病毒
, G% X6 Q0 P9 u4 C5 y2. AIDS ( acquired immunodeficiency syndrome ):获得性免疫缺陷综合征,艾滋病8 _+ O4 n0 w8 N, S
3. (be / come)on the market:出售% O$ w Q( W9 ^! x8 ~
4. Sustiva以及后面出现的Emtriva、Viread和Combivir都是治疗艾滋病药物的商品名。
3 I7 g& k) c; ~$ [# m t5. New England Journal of Medicine:新英格兰医药杂志。New England 是美国东北六州( Maine, Vermont, New Hampshire, Massachusetts, Rhode Island 和 Connecticut )的总称。 7 u2 K$ ^; X0 w6 B, v4 x
6. 英国英语中compare with是“与…相比较”的意思,compare to是“把...比作...” 的意思,但在美国英语中compare to也有compare with的意思,这里就是“把...与…相比较”的意思。 : a# O. d9 ?% U) o; S q g# J! O
7. AZT (Azidothymidine ):叠氨胸苷(能抑制引起艾滋病的人免疫缺陷病毒)
/ D t: B( i! e R2 O' i8. 3TC:拉夫米定(一种胞嘧啶核苷衍生物,能抑制乙肝病毒和人免疫缺陷病毒的逆转录酶的活性,改善肝脏组织的病变)) f& d2 @. w6 a m" D5 M) L
9. side effect:副作用来源:中国职称英语考试网+ r+ @ x. L- O
10. United States Food and Drug Administration (FDA):美国食品与药品管理局0 Q: N w$ ~8 R! y5 y+ \# a
11. birth disorder:先天性疾病+ \# Y) r# H4 C7 f7 @
. J8 s3 c7 \* A1 I8 l; b n练习:5 A9 W6 H* K9 D1 t9 }% U
1. A) conservation B) cooperation C) combinations D) considerations 4 q. l' ~) @1 W @) p& v2 G
2. A) simpler B) more complex C) more meaningless D) more troublesome |