Once-daily pill could simplify HIV treatment1 w6 o0 V/ r# h
9 \1 }: B) `- O7 k$ W4 WMyers Squibb and Gilead Sciences have combined many H.I.V. drugs into a single pill Sometimes the best medicine is more than one kind of medicine. Malaria, tuberculosis and H.I.V./AIDS,2 for example, are all treated with ____1____ of drugs. But that can mean a lot of pills to take. It would be ____2____ if drug companies combined all the medicines into a single pill, taken just once a day.
* T: c6 _0 `( t) D6 ~- M- FNow, two companies say they have done that for people just ____3____ treatment for H.I.V., the virus that causes AIDS. The companies are Bristol-Myers Squibb and Gilead Sciences. They have ____4____ a single pill that combines three drugs currently on the market.3 Bristol-Myers Squibb sells one of them ____5____ the name of Sustiva.4 Gilead combined the ____6____, Emtriva and Viread, into a single pill in two thousand four. 9 C/ Z9 j: [/ c! ~# O+ A& v t
Combining drugs involves more than ____7____ issues. It also involves issues of competition ____8____ the drugs are made by different companies. The new once-daily pill is the result of ____9____ is described as the first joint venture agreement of its kind in the treatment of H.I.V.
9 m; }+ a' |" t: v' q; C8 i8 P2 qIn January the New England Journal of Medicine5 published a study of the new pill. Researchers compared its ____10____ to6 that of the widely used combination of Sustiva and Combivir. Combivir ____11____ two drugs, AZT7 and 3TC.8 The researchers say that after one year of treatment, the new pill suppressed H.I.V. levels in more patients and with ____12____ side effects.9 Gilead paid for the study. Professor Joel Gallant at the Johns Hopkins School of Medicine in Baltimore, Maryland, led the research. He is a paid adviser to Gilead and Bristol-Meyers Squibb as well as the maker of Combivir, GlaxoSmithKline. 6 T) |! t5 I) {
Glaxo Smith Kline reacted ____13____ the findings by saying that a single study is of limited value. It says the effectiveness of Combivir has been shown in each of more than fifty studies.
J$ X% i5 }* K6 C! [4 T" ~- LThe price of the new once-daily pill has not been announced. But Gilead and Bristol-Myers Squibb say they will provide it at reduced cost to developing countries. They plan in the next few months to ask the United States Food and Drug Administration10 to ____14____ the new pill. 1 n! ~$ J5 }& g5 ], x
There are limits to who could take it because of the different drugs it contains. For example, ____15____ women are told not to take Sustiva because of the risk of birth disorders.11 Experts say more than forty million people around the world are living with H.I.V.& |, \/ R; l! l: P+ U6 ^) T
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词汇:
7 i; J2 F! F# ]; i$ [malaria n. 疟疾
- s! d: Z# f, Z) Y3 ?; { X8 ftuberculosis n. 结核(病)$ o. c' }" f$ V- c
joint adj. 联合的,共同的
3 Z6 O1 [/ X$ `$ l, \2 [4 psuppress vt. 抑制来源:中国职称英语考试网5 k$ ~* j1 d$ ~# H
pregnant adj. 妊娠的,有孕的1 J0 Q- ~! p: r! c6 e, w p
2 `. x/ X; o' t" n4 v) U2 u7 p% k
注释:' A+ s: P% f' O2 a8 W
1. HIV ( human immunodeficiency virus ):人免疫缺陷病毒
' I. J2 Z1 V" R) _4 g8 k! O2. AIDS ( acquired immunodeficiency syndrome ):获得性免疫缺陷综合征,艾滋病) ^$ Y) ~& N2 S3 X
3. (be / come)on the market:出售! l2 n; c9 j' Q: s# u& S9 _0 W O
4. Sustiva以及后面出现的Emtriva、Viread和Combivir都是治疗艾滋病药物的商品名。" D( c; F; A5 W$ s
5. New England Journal of Medicine:新英格兰医药杂志。New England 是美国东北六州( Maine, Vermont, New Hampshire, Massachusetts, Rhode Island 和 Connecticut )的总称。 ' r- Z. ^! S5 h. i! g
6. 英国英语中compare with是“与…相比较”的意思,compare to是“把...比作...” 的意思,但在美国英语中compare to也有compare with的意思,这里就是“把...与…相比较”的意思。
' U. p& v! l9 R7 u2 c7. AZT (Azidothymidine ):叠氨胸苷(能抑制引起艾滋病的人免疫缺陷病毒)
2 |( L% C/ W' k/ [6 ?& ? A8. 3TC:拉夫米定(一种胞嘧啶核苷衍生物,能抑制乙肝病毒和人免疫缺陷病毒的逆转录酶的活性,改善肝脏组织的病变)% x+ Q" T [" J/ x
9. side effect:副作用来源:中国职称英语考试网' s6 U6 T5 G7 ]5 H
10. United States Food and Drug Administration (FDA):美国食品与药品管理局
7 W- E4 ]3 \' x1 R11. birth disorder:先天性疾病7 `6 K* ] \; O& z
# d0 i+ _; M. S" l/ h _) h7 O) b
练习:( ?( X' O! G% {0 G* _
1. A) conservation B) cooperation C) combinations D) considerations
/ G9 c1 m/ J* L+ M7 v6 f2. A) simpler B) more complex C) more meaningless D) more troublesome |