Once-daily pill could simplify HIV treatment- y" z+ L; d7 |4 x
' ^2 D4 _7 @: h& @9 EMyers Squibb and Gilead Sciences have combined many H.I.V. drugs into a single pill Sometimes the best medicine is more than one kind of medicine. Malaria, tuberculosis and H.I.V./AIDS,2 for example, are all treated with ____1____ of drugs. But that can mean a lot of pills to take. It would be ____2____ if drug companies combined all the medicines into a single pill, taken just once a day.
6 j1 K- d/ `% h1 t: _5 {Now, two companies say they have done that for people just ____3____ treatment for H.I.V., the virus that causes AIDS. The companies are Bristol-Myers Squibb and Gilead Sciences. They have ____4____ a single pill that combines three drugs currently on the market.3 Bristol-Myers Squibb sells one of them ____5____ the name of Sustiva.4 Gilead combined the ____6____, Emtriva and Viread, into a single pill in two thousand four.
- M, b E0 @0 [Combining drugs involves more than ____7____ issues. It also involves issues of competition ____8____ the drugs are made by different companies. The new once-daily pill is the result of ____9____ is described as the first joint venture agreement of its kind in the treatment of H.I.V.
9 G* c2 [5 h4 T' `( MIn January the New England Journal of Medicine5 published a study of the new pill. Researchers compared its ____10____ to6 that of the widely used combination of Sustiva and Combivir. Combivir ____11____ two drugs, AZT7 and 3TC.8 The researchers say that after one year of treatment, the new pill suppressed H.I.V. levels in more patients and with ____12____ side effects.9 Gilead paid for the study. Professor Joel Gallant at the Johns Hopkins School of Medicine in Baltimore, Maryland, led the research. He is a paid adviser to Gilead and Bristol-Meyers Squibb as well as the maker of Combivir, GlaxoSmithKline.
G; _2 |4 _5 K }: n4 zGlaxo Smith Kline reacted ____13____ the findings by saying that a single study is of limited value. It says the effectiveness of Combivir has been shown in each of more than fifty studies. 0 d: w, G# ^# E- }7 q
The price of the new once-daily pill has not been announced. But Gilead and Bristol-Myers Squibb say they will provide it at reduced cost to developing countries. They plan in the next few months to ask the United States Food and Drug Administration10 to ____14____ the new pill.
3 y$ d1 a/ C/ i& N- s+ ~There are limits to who could take it because of the different drugs it contains. For example, ____15____ women are told not to take Sustiva because of the risk of birth disorders.11 Experts say more than forty million people around the world are living with H.I.V., ^; V, Y: K, m7 K
. z. \2 l1 v/ @: l( x4 z! c词汇:7 @& J3 t1 u# O
malaria n. 疟疾3 a2 p) e( N2 d
tuberculosis n. 结核(病)2 H6 `# U r! r8 W4 H* Z
joint adj. 联合的,共同的# |6 q8 v* i# f+ U9 Z
suppress vt. 抑制3 c: o% I4 B+ u* u
pregnant adj. 妊娠的,有孕的5 I* w7 {1 b% y
+ K; _7 Z, x9 ~2 {/ f' J注释:# ^7 Y* {5 j0 k2 m
1. HIV ( human immunodeficiency virus ):人免疫缺陷病毒5 B+ g2 d* q# t) s& g
2. AIDS ( acquired immunodeficiency syndrome ):获得性免疫缺陷综合征,艾滋病! x1 F0 V2 G$ W/ D) f. Q2 f/ P
3. (be / come)on the market:出售
4 r. H, V+ y6 }, m4. Sustiva以及后面出现的Emtriva、Viread和Combivir都是治疗艾滋病药物的商品名。
' x8 \4 G0 o/ e: I- e/ q, T5. New England Journal of Medicine:新英格兰医药杂志。New England 是美国东北六州( Maine, Vermont, New Hampshire, Massachusetts, Rhode Island 和 Connecticut )的总称。 8 F: j2 k; u3 O( z/ P* R* s( S
6. 英国英语中compare with是“与…相比较”的意思,compare to是“把...比作...” 的意思,但在美国英语中compare to也有compare with的意思,这里就是“把...与…相比较”的意思。
4 m- J5 ?7 g8 S: O, S. {7. AZT (Azidothymidine ):叠氨胸苷(能抑制引起艾滋病的人免疫缺陷病毒)4 f' I$ T2 x% U( l' n5 M) `
8. 3TC:拉夫米定(一种胞嘧啶核苷衍生物,能抑制乙肝病毒和人免疫缺陷病毒的逆转录酶的活性,改善肝脏组织的病变)3 s3 k. ^# ~/ E' j B5 C# M5 C
9. side effect:副作用/ `( e3 X s' c! P r0 n# t
10. United States Food and Drug Administration (FDA):美国食品与药品管理局! t) k h9 l7 A$ x( M5 `3 i# Y! v
11. birth disorder:先天性疾病
' ^1 R1 J6 j4 L. g 8 Y) i( ]' p G% D0 Y
练习:) u# U+ x9 v' x9 N: p( a2 v8 F% F
1. A) conservation B) cooperation C) combinations D) considerations 4 e$ P- V& b- {3 g* W, W! e; C |
2. A) simpler B) more complex C) more meaningless D) more troublesome 2 D8 `3 b8 B; l/ N$ A7 I
3. A) starting B) stopping C) ending D) discontinuing |