Children in areas affected by high levels of emissions, on average, scored more poorly on intelligence tests and were more prone to depression, anxiety and attention problems than children growing up in cleaner air, separate research teams in New York, Boston, Beijing, and Krakow, Poland, found. And older men and women long exposed to higher levels of traffic-related particles and ozone had memory and reasoning problems that effectively added five years to their mental age, other university researchers in Boston reported this year. The emissions may also heighten the risk of Alzheimer's disease and speed the effects of Parkinson's disease.
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+ G7 z0 X8 X; Y- h) k'The evidence is growing that air pollution can affect the brain,' says medical epidemiologist Heather Volk at USC's Keck School of Medicine. 'We may be starting to realize the effects are broader than we realized.'3 v m! ?2 ]: K6 x1 Z$ y
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Reviewing birth records, Dr. Volk and her colleagues calculated that children born to mothers living within 1,000 feet of a major road or freeway in Los Angeles, San Francisco or Sacramento were twice as likely to have autism, independent of gender, ethnicity and education level, as well as maternal age, exposure to tobacco smoke or other factors. The findings were published this year in the journal Environmental Health Perspectives.
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/ L1 u0 l9 r' Z8 x3 Q( r: c7 P'Based on our data, it looks like air pollution might be a risk factor for autism,' Dr. Volk says. Still, there are so many possible genetic and environmental influences that 'it is too soon for alarm,' she says.
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Exhaust fumes can extend farther from roadways than once thought. Traffic fumes from some major L.A. freeways reached up to 1.5 miles downwind─10 times farther than previously believed. And local weather patterns caused L.A. pollution levels to reach their most intense concentrations, not during normal rush hours, but in the hours before dawn when people are most likely to be at home, according to recent measurements by UCLA and USC researchers.0 V7 h9 E3 J1 o: _8 E* q
( {6 e. x5 I; K8 ?: hScientists believe that simple steps to speed traffic are a factor in reducing some public-health problems. In New Jersey, premature births, a risk factor for cognitive delays, in areas around highway toll plazas dropped 10.8% after the introduction of E-ZPass, which eased traffic congestion and reduced exhaust fumes, according to reports published in scientific journals this year and in 2009. The researchers, Princeton University economist Janet Currie and her colleagues at Columbia University, analyzed health data for the decade ending 2003.5 O2 ]; y5 F$ ^: W/ y6 D0 B
. N( [: F1 S: [' Y7 IAfter New York traffic managers rerouted streets in Times Square recently to lessen congestion, air-pollution levels in the vicinity dropped by 63%.
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7 C, m* _) p) Z8 E% OScientists are only beginning to understand the basic biology of car exhaust's toxic neural effects, especially from prenatal or lifetime exposures. 'It is hard to disentangle all the things in auto exhaust and sort out the effects of traffic from all the other possibilities,' says Dr. Currie, who studies the relationship between traffic and infant health.
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Researchers in Los Angeles, the U.S.'s most congested city, are studying lab mice raised on air piped in from a nearby freeway. They discovered that the particles inhaled by the mice─each particle less than one-thousandth the width of a human hair─somehow affected the brain, causing inflammation and altering neurochemistry among neurons involved in learning and memory.9 d' K h; L. x6 B! g* r& Y
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To study the effect of exhaust on expectant mothers, Frederica Perera at Columbia University's Center for Children's Environmental Health began in 1998 to equip hundreds of pregnant women with personal air monitors to measure the chemistry of the air they breathed. As the babies were born, Dr. Perera and colleagues tested some of the infants and discovered a distinctive biochemical mark in the DNA of about half of them, left by prenatal exposure to high levels of polycyclic aromatic hydrocarbons in exhaust.* r8 z- R- ^5 T3 r
# i1 d) [: l! IBy age 3, the children who were exposed prenatally to high exhaust levels were developing mental capacities fractionally more slowly. By age 5, their IQ scores averaged about four points lower on standard intelligence tests than those of less exposed children, the team reported in 2009. The differences, while small, were significant in terms of later educational development, the researchers said.
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By age 7, the children were more likely to show symptoms of anxiety, depression and attention problems, the researchers reported this year in Environmental Health Perspectives.% q X2 [- {8 W7 W% f2 x# \) Z
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'The mother's exposure─what she breathed into her lungs─could affect her child's later behavior,' Dr. Perera says. 'The placenta is not the perfect barrier we once thought.'
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拥堵的城市正快速成为科学家用来研究汽车废气对人类大脑影响的试管。
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如今的交通越来越拥堵,研究人员怀疑,各类轿车和卡车释放的尾气,特别是已经被证明会造成心脏病、癌症和呼吸道疾病的碳微粒,可能还会伤害对学习和记忆起关键作用的脑细胞及突触。& n) d' i$ i6 w" g
0 b5 Q9 e8 T3 [, g+ N9 r最新的公共卫生研究和实验室实验表明,在生命的每个阶段,汽车废气都会对人的心智能力、智力和情感稳定能力造成一定程度的损害。南加州大学(University of Southern California)流行病学专家Jiu-Chiuan Chen说,越来越多的科学家正在努力研究汽车尾气是否会损害人的大脑,以及为何会造成损害。他在研究交通污染对美国22个州7,500名女性大脑健康的影响。他说,这方面有关人类的数据还很新。$ `. D2 r4 a# E" l6 \! u1 k# O
, }) S1 f7 S, P' O! r' W没人知道经常吸入大量汽车尾气的上班族大脑是否会受到持续的影响。研究人员只是按照人们所居住的地点以及空气污染最严重的地区对潜在影响进行了研究。专家说,即便汽车尾气对司机的认知能力有慢性影响,可能也会由于影响太小而不容易得到可靠的测量,另外还可能会被压力、饮食或锻炼等其他对大脑有影响的健康因素所掩盖。) _6 v9 B- v9 X
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荷兰科学家最近发现,最近的研究表明,只要在一般的街道上吸入30分钟的尾气,就会导致控制行为、个性和决策的大脑区域加强脑电活动,这些变化是压力的迹象。哥伦比亚大学(Columbia University)和哈佛大学(Harvard University)的研究团队今年分别发布报告说,吸入含有大量汽车废气的普通城市的空气达到90天,就会改变老年人基因开启和关闭的方式;同时还会在新生婴儿的基因组中留下一个伴随其终身的分子标记。 |